Untargeted Profiling of Concordant/Discordant Phenotypes of High Insulin Resistance and Obesity To Predict the Risk of Developing Diabetes.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of proteome research"
DOI: 10.1021/acs.jproteome.7b00855
Abstract: This study explores the metabolic profiles of concordant/discordant phenotypes of high insulin resistance (IR) and obesity. Through untargeted metabolomics (LC-ESI-QTOF-MS), we analyzed the fasting serum of subjects with high IR and/or obesity ( n =… read more here.
Keywords: discordant phenotypes; high insulin; concordant discordant; insulin resistance ... See more keywords
Discordant phenotypes in twins with infantile nystagmus
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DOI: 10.1038/s41598-021-82368-0
Abstract: Infantile nystagmus (IN) may result from aetiologies including albinism and FRMD7 mutations. IN has low prevalence, and twins with IN are rare. Whilst discordant presentation has been previously reported for IN, we present for the… read more here.
Keywords: discordant phenotypes; monozygotic twins; infantile nystagmus; twins infantile ... See more keywords
Exploring the Genetic Causality of Discordant Phenotypes in Familial Apparently Balanced Translocation Cases Using Whole Exome Sequencing
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DOI: 10.3390/genes14010082
Abstract: Familial apparently balanced translocations (ABTs) are usually not associated with a phenotype; however, rarely, ABTs segregate with discordant phenotypes in family members carrying identical rearrangements. The current study was a follow-up investigation of four familial… read more here.
Keywords: discordant phenotypes; apparently balanced; phenotypes familial; whole exome ... See more keywords