Genetic studies discover novel coding and non-coding mutations in patients with Wilson's disease in China.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of clinical laboratory analysis"
DOI: 10.1002/jcla.24459
Abstract: OBJECTIVES Wilson disease (WD) is a rare autosomal recessive genetic disorder associated with various mutations in the ATP7B gene and leads to significant disability or death if untreated. Early diagnosis and proper therapy usually predict… read more here.
Keywords: atp7b gene; studies discover; genetic studies; wilson disease ... See more keywords
Computational Approaches to Discover Novel Natural Compounds for SARS‐CoV‐2 Therapeutics
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DOI: 10.1002/open.202000332
Abstract: Abstract Scientists all over the world are facing a challenging task of finding effective therapeutics for the coronavirus disease (COVID‐19). One of the fastest ways of finding putative drug candidates is the use of computational… read more here.
Keywords: natural compounds; discover novel; drug; approaches discover ... See more keywords
Using proteomics to discover novel biomarkers for fatty liver development and response to CB1R antagonist treatment in an obese mouse model
Sign Up to like & getrecommendations! Published in 2017 at "PROTEOMICS"
DOI: 10.1002/pmic.201600292
Abstract: Over activity of cannabinoid receptor type 1 (CB1R) plays a key role in increasing the incidence of obesity‐induced non‐alcoholic fatty liver disease. Tissue proteome analysis has been applied to investigate the bioinformatics regarding the mode… read more here.
Keywords: cb1r; fatty liver; treatment; discover novel ... See more keywords