Articles with "discovered scaffold" as a keyword



Thiazole‐Based IL‐17 Inhibitors Discovered by Scaffold Morphing

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Published in 2024 at "ChemMedChem"

DOI: 10.1002/cmdc.202400851

Abstract: The pro‐inflammatory cytokine interleukin‐17A (IL‐17) plays an important role in the body's defense against bacterial and fungal infections. However, overexpression of IL‐17 has been associated with several diseases, including rheumatoid arthritis, asthma, psoriasis, and even… read more here.

Keywords: based inhibitors; scaffold morphing; discovered scaffold; thiazole based ... See more keywords