Opportunities and Challenges in the Discovery of Allosteric Modulators of GPCRs.
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DOI: 10.1007/978-1-4939-7465-8_13
Abstract: From the pharmacological point of view, allosteric modulators may present numerous advantages over orthosteric ligands. Growing availability of novel tools and experimental data provides a tempting opportunity to apply computational methods to improve known modulators… read more here.
Keywords: modulators gpcrs; challenges discovery; allosteric modulators; opportunities challenges ... See more keywords