Drug Discovery Applications of Nitroso (Hetero)Arene Derivatives.
Sign Up to like & getrecommendations! Published in 2025 at "ChemPlusChem"
DOI: 10.1002/cplu.202500314
Abstract: Nitrosoarenes exhibit a variety of biological and pharmacological activities. This review uncovers their utility as therapeutic agents, which extends to oxidative stress regulation, DNA damage and repair interaction, cyclin‐dependent kinase inhibitors, anticancer, antiviral, antibacterial, antifungal,… read more here.
Keywords: nitroso hetero; hetero arene; discovery applications; arene derivatives ... See more keywords
Applications of chemogenomic library screening in drug discovery
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DOI: 10.1038/nrd.2016.244
Abstract: The allure of phenotypic screening, combined with the industry preference for target-based approaches, has prompted the development of innovative chemical biology technologies that facilitate the identification of new therapeutic targets for accelerated drug discovery. A… read more here.
Keywords: drug; discovery; chemogenomic library; discovery applications ... See more keywords
Applications of fluorine to the construction of bioisosteric elements for the purposes of novel drug discovery
Sign Up to like & getrecommendations! Published in 2021 at "Expert Opinion on Drug Discovery"
DOI: 10.1080/17460441.2021.1933427
Abstract: ABSTRACT Introduction There continues to be an exponential rise in the number of small molecule drugs that contain either a fluorine atom or a fluorinated fragment. While the unique properties of fluorine enable the precise… read more here.
Keywords: drug discovery; chemistry; applications fluorine; discovery applications ... See more keywords