Discovery of Carboline Derivatives as Potent Antifungal Agents for the Treatment of Cryptococcal Meningitis.
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DOI: 10.1021/acs.jmedchem.8b01598
Abstract: Clinical treatment of cryptococcal meningitis (CM) remains a significant challenge because of the lack of effective and safe drug therapies. Developing novel CM therapeutic agents with novel chemical scaffolds and new modes of action is… read more here.
Keywords: treatment cryptococcal; discovery carboline; compound; cryptococcal meningitis ... See more keywords