Articles with "discovery cftr" as a keyword



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Discovery of CFTR modulators for the treatment of cystic fibrosis

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Published in 2021 at "Expert Opinion on Drug Discovery"

DOI: 10.1080/17460441.2021.1912732

Abstract: ABSTRACT Introduction Cystic fibrosis (CF) is a life-threatening inherited disease caused by mutations in the gene encoding the CF transmembrane conductance regulator (CFTR) protein, an anion channel expressed at the apical membrane of secretory epithelia.… read more here.

Keywords: cftr; cftr modulators; cystic fibrosis; discovery cftr ... See more keywords