Articles with "discovery cytotoxic" as a keyword



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Target discovery of cytotoxic withanolides from Physalis angulata var. villosa via reactivity‐based screening

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Published in 2018 at "Journal of Pharmaceutical and Biomedical Analysis"

DOI: 10.1016/j.jpba.2017.12.047

Abstract: Graphical abstract Figure. No caption available. HighlightsThe reactivity‐based screening (RBS) approach was developed.Thiol probe targeted withanolides via the nucleophilic addition to 2(3)‐en‐1‐one.Eleven cytotoxic withanolides were discovered from plant extract directed by RBS. ABSTRACT The reactivity‐based… read more here.

Keywords: cytotoxic withanolides; discovery cytotoxic; cytotoxic; reactivity based ... See more keywords