Discovery of Desmuramylpeptide NOD2 Agonists with Single-Digit Nanomolar Potency
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DOI: 10.1021/acsmedchemlett.2c00121
Abstract: The innate immune receptor nucleotide-binding oligomerization-domain-containing protein 2 (NOD2) represents an important target for the development of structurally defined small molecule immunomodulatory compounds that have great potential to be used either as vaccine adjuvants or… read more here.
Keywords: nod2 agonists; single digit; agonists single; discovery desmuramylpeptide ... See more keywords