Fifty years of lyase and a moment of truth: sphingosine phosphate lyase from discovery to disease[S]
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DOI: 10.1194/jlr.s091181
Abstract: Sphingosine phosphate lyase (SPL) is the final enzyme in the sphingolipid degradative pathway, catalyzing the irreversible cleavage of long-chain base phosphates (LCBPs) to yield a long-chain aldehyde and ethanolamine phosphate (EP). SPL guards the sole… read more here.
Keywords: phosphate; spl; discovery disease; sphingosine phosphate ... See more keywords