Approaches for the discovery of drugs that target K Na 1.1 channels in KCNT1-associated epilepsy
Sign Up to like & getrecommendations! Published in 2022 at "Expert Opinion on Drug Discovery"
DOI: 10.1080/17460441.2023.2150164
Abstract: ABSTRACT Introduction There are approximately 70 million people with epilepsy and about 30% of patients are not satisfactorily treated. A link between gene mutations and epilepsy is well documented. A number of pathological variants of… read more here.
Keywords: gene mutations; discovery drugs; approaches discovery; kcnt1 gene ... See more keywords
Intracellular Antibodies for Drug Discovery and as Drugs of the Future
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DOI: 10.3390/antib12010024
Abstract: The application of antibodies in cells was first shown in the early 1990s, and subsequently, the field of intracellular antibodies has expanded to encompass antibody fragments and their use in target validation and as engineered… read more here.
Keywords: drug discovery; antibodies drug; discovery drugs; drug ... See more keywords