Articles with "discovery ethoxy" as a keyword



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Discovery of 4-((2S,4S)-4-Ethoxy-1-((5-methoxy-7-methyl-1H-indol-4-yl)methyl)piperidin-2-yl)benzoic Acid (LNP023), a Factor B Inhibitor Specifically Designed To Be Applicable to Treating a Diverse Array of Complement Mediated Diseases.

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Published in 2020 at "Journal of medicinal chemistry"

DOI: 10.1021/acs.jmedchem.9b01870

Abstract: The alternative pathway (AP) of the complement system is a key contributor to the pathogenesis of several human diseases including age-related macular degeneration, paroxysmal nocturnal hemoglobinuria (PNH), atypical hemolytic uremic syndrome (aHUS), and various glomerular… read more here.

Keywords: methyl; methoxy methyl; complement; ethoxy methoxy ... See more keywords