Phage-based target discovery and its exploitation towards novel antibacterial molecules.
Sign Up to like & getrecommendations! Published in 2020 at "Current opinion in biotechnology"
DOI: 10.1016/j.copbio.2020.08.015
Abstract: The deeply intertwined evolutionary history between bacteriophages and bacteria has endowed phages with highly specific mechanisms to hijack bacterial cell metabolism for their propagation. Here, we present a comprehensive, phage-driven strategy to reveal novel antibacterial… read more here.
Keywords: novel antibacterial; discovery exploitation; based target; phage ... See more keywords