Discovery of GPR84 Fluorogenic Probes Based on a Novel Antagonist for GPR84 Bioimaging.
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DOI: 10.1021/acs.jmedchem.4c00359
Abstract: GPR84 is a promising therapeutic target and biomarker for a range of diseases. In this study, we reported the discovery of BINOL phosphate (BINOP) derivatives as GPR84 antagonists. By investigating the structure-activity relationship, we identified… read more here.
Keywords: fluorogenic probes; gpr84; discovery gpr84; gpr84 fluorogenic ... See more keywords