Machine Learning for Discovery of GSK3β Inhibitors
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DOI: 10.1021/acsomega.0c03302
Abstract: Alzheimer’s disease (AD) is the most common cause of dementia, affecting approximately 35 million people worldwide. The current treatment options for people with AD consist of drugs designed to slow the rate of decline in… read more here.
Keywords: learning discovery; machine; discovery gsk3; machine learning ... See more keywords
Discovery of GSK3β Inhibitors through In Silico Prediction-and-Experiment Cycling Strategy, and Biological Evaluation
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DOI: 10.3390/molecules27123825
Abstract: Direct inhibitors of glycogen synthase kinase 3β (GSK3β) have been investigated and reported for the past 20 years. In the search for novel scaffold inhibitors, 3000 compounds were selected through structure-based virtual screening (SBVS), and… read more here.
Keywords: gsk3 inhibitors; silico prediction; inhibitors silico; gsk3 ... See more keywords