Fragment‐based drug discovery—the importance of high‐quality molecule libraries
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Oncology"
DOI: 10.1002/1878-0261.13277
Abstract: Fragment‐based drug discovery (FBDD) is now established as a complementary approach to high‐throughput screening (HTS). Contrary to HTS, where large libraries of drug‐like molecules are screened, FBDD screens involve smaller and less complex molecules which,… read more here.
Keywords: fragment based; drug discovery; based drug; discovery importance ... See more keywords
The discovery and importance of genomic imprinting
Sign Up to like & getrecommendations! Published in 2018 at "eLife"
DOI: 10.7554/elife.42368
Abstract: The discovery of genomic imprinting by Davor Solter, Azim Surani and co-workers in the mid-1980s has provided a foundation for the study of epigenetic inheritance and the epigenetic control of gene activity and repression, especially… read more here.
Keywords: genomic imprinting; discovery; discovery importance; importance genomic ... See more keywords