Discovery and molecular characterization of a novel trichovirus infecting sweet cherry
Sign Up to like & getrecommendations! Published in 2020 at "Virus Genes"
DOI: 10.1007/s11262-020-01743-7
Abstract: Contigs with the highest sequence similarity (73%) to Apricot pseudo-chlorotic leaf spot virus (genus Trichovirus , family Betaflexiviridae ) were identified by high-throughput sequencing from a symptomless sweet cherry accession. The complete genome sequence of… read more here.
Keywords: characterization novel; molecular characterization; trichovirus; discovery molecular ... See more keywords
Discovery, molecular dynamic simulation and biological evaluation of structurally diverse cholinesterase inhibitors with new scaffold through shape-based pharmacophore virtual screening.
Sign Up to like & getrecommendations! Published in 2019 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2019.103294
Abstract: Designing small molecule inhibitors targeting cholinesterases (ChEs) is considered as an efficient strategy for the treatment of Alzheimer's disease (AD). In the present study, based on a shaped-based pharmacophore (SBP) model that we reported previously,… read more here.
Keywords: virtual screening; based pharmacophore; value; discovery molecular ... See more keywords
Mutual interactors as a principle for phenotype discovery in molecular interaction networks.
Sign Up to like & getrecommendations! Published in 2022 at "Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing"
DOI: 10.1142/9789811270611_0007
Abstract: Biological networks are powerful representations for the discovery of molecular phenotypes. Fundamental to network analysis is the principle-rooted in social networks-that nodes that interact in the network tend to have similar properties. While this long-standing… read more here.
Keywords: interaction; network; principle phenotype; interactors principle ... See more keywords