Discovery of Pemigatinib: A Potent and Selective Fibroblast Growth Factor Receptor (FGFR) Inhibitor.
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DOI: 10.1021/acs.jmedchem.1c00713
Abstract: Aberrant activation of FGFR has been linked to the pathogenesis of many tumor types. Selective inhibition of FGFR has emerged as a promising approach for cancer treatment. Herein, we describe the discovery of compound 38… read more here.
Keywords: potent selective; inhibitor; pemigatinib; fgfr ... See more keywords