Computational methods to assist in the discovery of pharmacological chaperones for rare diseases
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DOI: 10.1093/bib/bbac198
Abstract: Pharmacological chaperones are chemical compounds able to bind proteins and stabilize them against denaturation and following degradation. Some pharmacological chaperones have been approved, or are under investigation, for the treatment of rare inborn errors of… read more here.
Keywords: discovery pharmacological; assist discovery; pharmacological chaperones; computational methods ... See more keywords