Discovery of a phase-separating small molecule that selectively sequesters tubulin in cells
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DOI: 10.1039/d1sc07151c
Abstract: Phase-separated membraneless organelles or biomolecular condensates play diverse functions in cells, however recapturing their characteristics using small organic molecules has been a challenge. In the present study, cell-lysate-based screening of 843 self-assembling small molecules led… read more here.
Keywords: small molecule; phase separating; discovery phase; molecule ... See more keywords