Target Discovery for Precision Medicine Using High-Throughput Genome Engineering.
Sign Up to like & getrecommendations! Published in 2017 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-319-63904-8_7
Abstract: Over the past few years, programmable RNA-guided nucleases such as the CRISPR/Cas9 system have ushered in a new era of precision genome editing in diverse model systems and in human cells. Functional screens using large… read more here.
Keywords: medicine; discovery precision; target discovery; high throughput ... See more keywords
Immunotherapy efficacy and gender: discovery in precision medicine.
Sign Up to like & getrecommendations! Published in 2018 at "Translational lung cancer research"
DOI: 10.21037/tlcr.2018.08.05
Abstract: Immunotherapy is transforming the care of cancer. In the past five years, checkpoint blockade agents targeting the PD-1/PD-L1 checkpoint (e.g., nivolumab, pembrolizumab) have garnered FDA approvals in diverse indications including melanoma, non-small cell lung cancer… read more here.
Keywords: medicine; discovery precision; immunotherapy; efficacy gender ... See more keywords