Discovery of G Protein-Biased Ligands against 5-HT7R.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.1c00110
Abstract: There has been significant attention concerning the biased agonism of G protein-coupled receptors (GPCRs), and it has resulted in various pharmacological benefits. 5-HT7R belongs to a GPCR, and it is a promising pharmaceutical target for… read more here.
Keywords: protein; biased ligands; ligands ht7r; discovery protein ... See more keywords
The discovery of protein biomarkers in pre-eclampsia: the promising role of mass spectrometry
Sign Up to like & getrecommendations! Published in 2018 at "Biomarkers"
DOI: 10.1080/1354750x.2018.1474257
Abstract: Abstract Context: Pre-eclampsia (PE) is a common hypertensive disorder of pregnancy that substantially affects maternal and neonatal morbidity and mortality worldwide. The aetiology of the disease remains poorly understood with lack of reliable diagnostic tests.… read more here.
Keywords: protein; pre eclampsia; discovery protein; mass spectrometry ... See more keywords