Discovery of pyrrole derivatives as acetylcholinesterase-sparing butyrylcholinesterase inhibitor
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DOI: 10.3389/fphar.2022.1043397
Abstract: Inspired by the crucial roles of (hetero)aryl rings in cholinesterase inhibitors and the pyrrole ring in new drug discovery, we synthesized 19 pyrrole derivatives and investigated their cholinesterase inhibitory activity. As a result, compounds 3o,… read more here.
Keywords: discovery pyrrole; acetylcholinesterase sparing; sparing butyrylcholinesterase; inhibitor ... See more keywords