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Published in 2019 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.9b01275
Abstract: Trypanosoma cruzi is the causative pathogen of Chagas disease and the main culprit for cardiac-related mortality in Latin-America triggered by an infective agent. Uncapable of synthesizing purines de novo, this parasite depends on acquisition and…
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Keywords:
pyridine dideazapurine;
pyrrolo pyridine;
nucleoside analogues;
trypanosoma cruzi ... See more keywords