Cardiovascular disease models: A game changing paradigm in drug discovery and screening.
Sign Up to like & getrecommendations! Published in 2019 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2018.09.036
Abstract: Cardiovascular disease is the leading cause of death worldwide. Although investment in drug discovery and development has been sky-rocketing, the number of approved drugs has been declining. Cardiovascular toxicity due to therapeutic drug use claims… read more here.
Keywords: drug; discovery; discovery screening; drug discovery ... See more keywords
Screening Approaches for Targeting Ribonucleoprotein Complexes: A New Dimension for Drug Discovery
Sign Up to like & getrecommendations! Published in 2019 at "SLAS Discovery"
DOI: 10.1177/2472555218818065
Abstract: RNA-binding proteins (RBPs) are pleiotropic factors that control the processing and functional compartmentalization of transcripts by binding primarily to mRNA untranslated regions (UTRs). The competitive and/or cooperative interplay between RBPs and an array of coding… read more here.
Keywords: targeting ribonucleoprotein; screening approaches; approaches targeting; rna ... See more keywords