Discovery of 9,11-Seco-Cholesterol Derivatives as Novel FXR Antagonists
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DOI: 10.1021/acsomega.2c01567
Abstract: The farnesoid X receptor (FXR) plays an important role in the regulation of bile acid, lipid, and glucose homeostasis. Recent findings have shown that the inhibition of FXR is beneficial to improvement of related metabolic… read more here.
Keywords: discovery seco; seco cholesterol; derivatives novel; fxr antagonists ... See more keywords