Discovery of Selenium-Containing STING Agonists as Orally Available Antitumor Agents.
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DOI: 10.1021/acs.jmedchem.2c00634
Abstract: Activation of the stimulator of interferon genes (STING) pathway to achieve antitumor response is an attractive approach for cancer immunotherapy. In this study, we report the identification of BSP16 (LF250) as a potent, orally available… read more here.
Keywords: selenium containing; antitumor; sting agonists; orally available ... See more keywords