Discovery of a simple iron catalyst reveals the intimate steps of C–H amination to form C–N bonds
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DOI: 10.1039/d2sc04170g
Abstract: Formation of ubiquitous C–N bonds traditionally uses prefunctionalized carbon precursors. Recently, metal-catalyzed amination of unfunctionalized C–H bonds with azides has become an attractive and atom-economic strategy for C–N bond formation, though all catalysts contain sophisticated… read more here.
Keywords: discovery simple; catalyst; iron; intimate steps ... See more keywords
Discovery of Simple Diacylhydrazine-Functionalized Cinnamic Acid Derivatives as Potential Microtubule Stabilizers
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DOI: 10.3390/ijms232012365
Abstract: To develop novel microtubule-binding agents for cancer therapy, an array of N-cinnamoyl-N’-(substituted)acryloyl hydrazide derivatives were facilely synthesized through a two-step process. Initially, the antiproliferative activity of these title compounds was explored against A549, 98 PC-3… read more here.
Keywords: discovery simple; microtubule stabilizers; compound i23; potential microtubule ... See more keywords