Articles with "discovery sulfonamide" as a keyword



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Discovery of sulfonamide-tethered isatin derivatives as novel anticancer agents and VEGFR-2 inhibitors

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Published in 2023 at "Journal of Enzyme Inhibition and Medicinal Chemistry"

DOI: 10.1080/14756366.2023.2203389

Abstract: Abstract In this work, new isatin-based sulphonamides (6a-i, 11a-c, 12a-c) were designed and synthesised as potential dual VEGFR-2 and carbonic anhydrase inhibitors with anticancer activities. Firstly, all target isatins were examined for in vitro antitumor… read more here.

Keywords: discovery sulfonamide; sulfonamide tethered; isatin derivatives; derivatives novel ... See more keywords