Discovery of Sulforaphane as a Potent BACE1 Inhibitor Based on Kinetics and Computational Studies
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DOI: 10.3390/nu12103026
Abstract: BACE1 is the rate-limiting enzyme involved in the production and deposition of β-amyloid (Aβ). Since neurotoxic Aβ plays a critical role in Alzheimer’s disease (AD) pathogenesis, BACE1 has emerged as a key target for preventing… read more here.
Keywords: discovery sulforaphane; bace1 inhibitor; sulforaphane; potent ... See more keywords