Is Targeting the Inflammasome a Way Forward for Neuroscience Drug Discovery?
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DOI: 10.1177/2472555218786210
Abstract: Neuroinflammation is becoming increasingly recognized as a critical factor in the pathology of both acute and chronic neurological conditions. Inflammasomes such as the one formed by NACHT, LRR, and PYD domains containing protein 3 (NLRP3)… read more here.
Keywords: discovery targeting; pathology; drug; inflammasome way ... See more keywords
Antiviral drug discovery by targeting the SARS-CoV-2 polyprotein processing by inhibition of the main protease
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DOI: 10.7717/peerj.12929
Abstract: The spread of SARS-CoV-2, the causative agent for COVID-19, has led to a global and deadly pandemic. To date, few drugs have been approved for treating SARS-CoV-2 infections. In this study, a structure-based approach was… read more here.
Keywords: drug discovery; targeting sars; main protease; discovery targeting ... See more keywords