Discovery of [1,2,4]triazolo[1,5-a]pyrimidines derivatives as potential anticancer agents.
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DOI: 10.1016/j.ejmech.2020.113108
Abstract: In this work, we reported the discovery of compound 6i with potent antiproliferative activity against MGC-803. Among these compounds, the most potent compound 6i could effectively inhibit MGC-803 (IC50 = 0.96 μM), being around 38-fold selectivity over GES-1.… read more here.
Keywords: mgc 803; discovery triazolo; triazolo pyrimidines; derivatives potential ... See more keywords