Identification of new IDH2R140Q inhibitors by discriminatory analysis‐based molecular docking and biological evaluation
Sign Up to like & getrecommendations! Published in 2020 at "Archiv der Pharmazie"
DOI: 10.1002/ardp.202000063
Abstract: Isocitrate dehydrogenase 2 (IDH2) is a key enzyme in the regulation of cell metabolism. Its mutated type can lead to the accumulation of 2‐hydroxyglutarate, which is often related to malignancies such as acute myeloid leukemia.… read more here.
Keywords: new idh2r140q; analysis based; idh2r140q inhibitors; based molecular ... See more keywords