Disease aggressiveness signatures of amyotrophic lateral sclerosis in white matter tracts revealed by the D50 disease progression model
Sign Up to like & getrecommendations! Published in 2020 at "Human Brain Mapping"
DOI: 10.1002/hbm.25258
Abstract: Numerous neuroimaging studies in amyotrophic lateral sclerosis (ALS) have reported links between structural changes and clinical data; however phenotypic and disease course heterogeneity have occluded robust associations. The present study used the novel D50 model,… read more here.
Keywords: disease aggressiveness; disease; pathology; amyotrophic lateral ... See more keywords
Predictors of disease aggressiveness influence outcome from immunotherapy treatment in renal clear cell carcinoma
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DOI: 10.1080/2162402x.2018.1500106
Abstract: ABSTRACT Renal clear cell carcinoma (RCC) is the most common type of kidney cancer and has a high propensity for metastasis. While treatment with immune checkpoint inhibitors, such as anti-PD-1, have shown modest improvements in… read more here.
Keywords: disease aggressiveness; cell carcinoma; treatment; clear cell ... See more keywords
Abstract 7377: Deep learning uncovers morphological patterns of YAP1/TEAD activity related to disease aggressiveness in cancer patients
Sign Up to like & getrecommendations! Published in 2024 at "Cancer Research"
DOI: 10.1158/1538-7445.am2024-7377
Abstract: Hippo signaling emerged over the last decade as a major tumor-suppressing pathway. Its dysregulation is generally associated with abnormal expression levels of YAP1, WWTR1 (coding for the TAZ protein) and TEAD genes among others. This… read more here.
Keywords: deep learning; cancer; disease aggressiveness; tead activity ... See more keywords