Bacterial Butyrate in Parkinson's Disease Is Linked to Epigenetic Changes and Depressive Symptoms
Sign Up to like & getrecommendations! Published in 2022 at "Movement Disorders"
DOI: 10.1002/mds.29128
Abstract: The gut microbiome and its metabolites can impact brain health and are altered in Parkinson's disease (PD) patients. It has been recently demonstrated that PD patients have reduced fecal levels of the potent epigenetic modulator… read more here.
Keywords: butyrate parkinson; disease; parkinson disease; disease linked ... See more keywords
RNA recognition motifs of disease-linked RNA-binding proteins contribute to amyloid formation
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-42367-8
Abstract: Aberrant expression, dysfunction and particularly aggregation of a group of RNA-binding proteins, including TDP-43, FUS and RBM45, are associated with neurological disorders. These three disease-linked RNA-binding proteins all contain at least one RNA recognition motif… read more here.
Keywords: binding proteins; rna binding; disease; disease linked ... See more keywords
Disease-Linked SHP2 Mutations Cause Phase Separation to Activate MAPK.
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DOI: 10.1158/2159-8290.cd-rw2020-147
Abstract: SHP2 mutations causing juvenile leukemia and other diseases led to activating SHP2 phase separation. read more here.
Keywords: shp2 mutations; mutations cause; phase separation; linked shp2 ... See more keywords