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Can GBA1-Associated Parkinson Disease Be Modeled in the Mouse?

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1 Published in 2019 at "Trends in Neurosciences"

DOI: 10.1016/j.tins.2019.05.010

Abstract: Homozygous and heterozygous mutations in GBA1, the gene implicated in Gaucher disease, increase the risk and severity of Parkinson disease (PD). We evaluated the design, phenotype, strengths, and limitations of current GBA1-associated PD mouse models.… read more here.

Keywords: gba1 associated; disease modeled; associated parkinson; modeled mouse ... See more keywords