Comparative Risk of Alzheimer Disease and Related Dementia Among Medicare Beneficiaries With Rheumatoid Arthritis Treated With Targeted Disease-Modifying Antirheumatic Agents
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.6567
Abstract: Key Points Question Is use of targeted disease-modifying antirheumatic drugs associated with risk of Alzheimer disease and related dementia (ADRD)? Findings In this cohort study including 22 569 propensity score–matched patient pairs, initiation of inhibitors of… read more here.
Keywords: risk alzheimer; disease; targeted disease; disease modifying ... See more keywords
Real‐World Effectiveness of Initial Disease‐Modifying Therapies in Pediatric Multiple Sclerosis
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DOI: 10.1002/ana.25737
Abstract: To assess real‐world effectiveness of initial treatment with newer compared to injectable disease‐modifying therapies (DMTs) on disease activity in pediatric multiple sclerosis (MS) and clinically isolated syndrome (CIS). read more here.
Keywords: real world; effectiveness initial; world effectiveness; modifying therapies ... See more keywords
Biomarker‐driven phenotyping in Parkinson's disease: A translational missing link in disease‐modifying clinical trials
Sign Up to like & getrecommendations! Published in 2017 at "Movement Disorders"
DOI: 10.1002/mds.26913
Abstract: Past clinical trials of putative neuroprotective therapies have targeted PD as a single pathogenic disease entity. From an Oslerian clinicopathological perspective, the wide complexity of PD converges into Lewy bodies and justifies a reductionist approach… read more here.
Keywords: medicine; parkinson; disease modifying; disease ... See more keywords
Use and safety of disease‐modifying therapy in pregnant women with multiple sclerosis
Sign Up to like & getrecommendations! Published in 2019 at "Pharmacoepidemiology and Drug Safety"
DOI: 10.1002/pds.4735
Abstract: The purpose of this study is to describe dispensing patterns and comparative safety of disease‐modifying therapies (DMTs) during pregnancy in women with multiple sclerosis (MS). read more here.
Keywords: women multiple; safety; disease modifying; safety disease ... See more keywords
Trends in the use of disease‐modifying therapies among reproductive‐aged women with multiple sclerosis in the United States from 2010 to 2019
Sign Up to like & getrecommendations! Published in 2022 at "Pharmacoepidemiology and Drug Safety"
DOI: 10.1002/pds.5411
Abstract: Multiple sclerosis (MS) is a chronic disease of the central nervous system that disproportionately affects women, with typical onset during reproductive age. Several disease‐modifying therapies (DMTs) are FDA‐approved to slow disease progression, but are not… read more here.
Keywords: modifying therapies; 2010 2019; disease modifying; multiple sclerosis ... See more keywords
Biological disease‐modifying drugs for rheumatoid arthritis
Sign Up to like & getrecommendations! Published in 2020 at "Prescriber"
DOI: 10.1002/psb.1836
Abstract: There are now nine biological disease‐modifying antirheumatic drugs (bDMARDs) available for the treatment of rheumatoid arthritis – seven monoclonal antibodies and two fusion proteins. This article summarises their indications, efficacy, place in therapy and adverse… read more here.
Keywords: drugs rheumatoid; disease modifying; biological disease; rheumatoid arthritis ... See more keywords
[Disease-modifying treatment approaches for Alzheimer's disease].
Sign Up to like & getrecommendations! Published in 2021 at "Der Nervenarzt"
DOI: 10.1007/s00115-021-01222-w
Abstract: Alzheimer's disease is one the major common diseases but so far only with symptomatic treatment options. New insights define the disease as a slowly progressive continuum with very long preclinical and early symptomatic phases. Innovative molecular… read more here.
Keywords: alzheimer disease; treatment; disease modifying; disease ... See more keywords
Use of biological disease modifying antirheumatic drugs in rheumatoid arthritis in Austria from 2008 to 2011
Sign Up to like & getrecommendations! Published in 2018 at "Wiener klinische Wochenschrift"
DOI: 10.1007/s00508-018-1321-4
Abstract: SummaryBackgroundRheumatoid arthritis (RA) is the most prevalent chronic inflammatory joint disease. On a national level in Austria, there are currently no data available on how often and which biological disease modifying antirheumatic drugs (bDMARDs) are prescribed… read more here.
Keywords: modifying antirheumatic; drug survival; disease modifying; biological disease ... See more keywords
Assessment of adherence to disease-modifying anti-rheumatic drugs in rheumatoid arthritis
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DOI: 10.1007/s10067-019-04837-2
Abstract: Objectives This work aimed to assess treatment adherence in rheumatoid arthritis patients with several tools and to identify factors associated with poor adherence. Method Between February and December 2015, 183 patients were included in this… read more here.
Keywords: mmas; disease modifying; rheumatoid arthritis; adherence ... See more keywords
Transplantation as disease modifying therapy in adults with inherited metabolic disorders
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Inherited Metabolic Disease"
DOI: 10.1007/s10545-018-0141-z
Abstract: Transplantation is an established disease modifying therapy in selected children with certain inherited metabolic diseases (IMDs). Transplantation of hematopoietic stem cells or solid organs can be used to partially correct the underlying metabolic defect, address… read more here.
Keywords: disease modifying; disease; inherited metabolic; transplantation ... See more keywords
Real-life data of survival and reasons for discontinuation of biological disease-modifying drugs ‘in’ rheumatoid arthritis
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Clinical Pharmacy"
DOI: 10.1007/s11096-020-01171-5
Abstract: Background Rheumatoid arthritis is a chronic, autoimmune disease in which treatment has evolved with a variety of therapeutic classes. Biological disease-modifying antirheumatic drugs have improved therapy; however, the continued long-term use of these drugs with… read more here.
Keywords: disease modifying; disease; biological disease; rheumatoid arthritis ... See more keywords