Validation and interpretation of IGH and TCR clonality testing by Ion Torrent S5 NGS for diagnosis and disease monitoring in B and T cell cancers
Sign Up to like & getrecommendations! Published in 2020 at "Practical Laboratory Medicine"
DOI: 10.1016/j.plabm.2020.e00191
Abstract: Cancers of B and T lymphocytes are the most common hematologic malignancies in the US. Molecular assays for assessing clonal rearrangements of the immunoglobulin receptor (IGH) and T-cell receptor (TCR), commonly referred to as B-… read more here.
Keywords: disease monitoring; clonality; ion; cell ... See more keywords
PS02.083: CIRCULATING CELL FREE TUMOR DNA FOR DISEASE MONITORING AFTER NEOADJUVANT CHEMORADIOTHERAPY FOR ESOPHAGEAL CANCER: PROOF-OF-PRINCIPLE
Sign Up to like & getrecommendations! Published in 2018 at "Diseases of the Esophagus"
DOI: 10.1093/dote/doy089.ps02.083
Abstract: An active surveillance approach has been proposed for patients with a clinically complete response (cCR) after neoadjuvant chemoradiotherapy (nCRT) in esophageal cancer (SANO trial). To justify renouncing surgical resection, patients with residual disease after nCRT… read more here.
Keywords: esophageal cancer; disease; cell free; disease monitoring ... See more keywords
Non‐invasive diagnosis of cirrhosis and long‐term disease monitoring by transient elastography in patients with Wilson disease
Sign Up to like & getrecommendations! Published in 2020 at "Liver International"
DOI: 10.1111/liv.14368
Abstract: The value of liver stiffness measurement (LSM) by transient elastography (TE) for non‐invasive fibrosis staging and disease monitoring has not been established in patients with Wilson disease (WD). read more here.
Keywords: patients wilson; transient elastography; disease; non invasive ... See more keywords
Abstract 2224: Applying optical genome mapping to detect genomic biomarkers and use for residual disease monitoring in hematologic malignancies
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-2224
Abstract: Disease monitoring is important to detect cancer relapse, often as a result of a treatment-surviving cancer cell population. Detection of relapse is critical to determine the intensity and length of treatments and to predict the… read more here.
Keywords: optical genome; genome mapping; cancer; disease monitoring ... See more keywords
Current noninvasive modalities in Crohn’s disease monitoring
Sign Up to like & getrecommendations! Published in 2021 at "Annals of Gastroenterology"
DOI: 10.20524/aog.2021.0648
Abstract: Crohn’s disease (CD) is characterized by a remitting and relapsing course. Longstanding active CD may result in accumulating intestinal damage and disease-related complications. In contrast, mucosal healing is associated with significant improvement in the health-related… read more here.
Keywords: current noninvasive; modalities crohn; disease; noninvasive modalities ... See more keywords
Serum cytokines predict efficacy and toxicity, but are not useful for disease monitoring in lung cancer treated with PD-(L)1 inhibitors
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.1010660
Abstract: Introduction PD-(L)1 inhibitors (IO) have improved the prognosis of non-small-cell lung cancer (NSCLC), but more reliable predictors of efficacy and immune-related adverse events (irAE) are urgently needed. Cytokines are important effector molecules of the immune… read more here.
Keywords: lung cancer; serum; disease monitoring;