Association of TDP-43 proteinopathy, cerebral amyloid angiopathy, and Lewy bodies with cognitive impairment in individuals with or without Alzheimer’s disease neuropathology
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DOI: 10.1038/s41598-020-71305-2
Abstract: Alzheimer’s disease patients typically present with multiple co-morbid neuropathologies at autopsy, but the impact of these pathologies on cognitive impairment during life is poorly understood. In this study, we developed cognitive trajectories for patients with… read more here.
Keywords: alzheimer disease; disease; disease neuropathology; cognitive impairment ... See more keywords
Expression of INPP5D Isoforms in Human Brain: Impact of Alzheimer’s Disease Neuropathology and Genetics
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DOI: 10.3390/genes14030763
Abstract: The single nucleotide polymorphisms rs35349669 and rs10933431 within Inositol Polyphosphate-5-Phosphatase D (INPP5D) are strongly associated with Alzheimer’s Disease risk. To better understand INPP5D expression in the brain, we investigated INPP5D isoform expression as a function… read more here.
Keywords: disease neuropathology; alzheimer disease; inpp5d; expression ... See more keywords