Marginal, conditional, and pseudo likelihood ratio approaches for biomarker combination to predict a binary disease outcome
Sign Up to like & getrecommendations! Published in 2022 at "Statistics in Medicine"
DOI: 10.1002/sim.9371
Abstract: It is a common practice in public health research that multiple biomarkers are collected to diagnose or predict a disease outcome. A natural question is how to combine multiple biomarkers to improve the diagnostic accuracy.… read more here.
Keywords: likelihood ratio; biomarker combination; likelihood; disease outcome ... See more keywords
Restrained expression of canine glucocorticoid receptor splice variants α and P prognosticates fatal disease outcome in SIRS
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-03451-0
Abstract: Glucocorticoids play a central role in the inflammatory response and alleviate the symptoms in critically ill patients. The glucocorticoid action relies on the glucocorticoid receptor (GR) which translocates into the nucleus upon ligand-binding and regulates… read more here.
Keywords: expression; glucocorticoid receptor; splice variants; cgr ... See more keywords
Proteomics Analysis Reveals Protein Panels That Are Associated with Prediction to Tyrosine Kinase Inhibitors Response, Bone Marrow Transplant, Survival and Disease Outcome of Chronic Myeloid Leukemia Patients
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DOI: 10.1182/blood-2018-99-118754
Abstract: Clinical and molecular diagnosis of most hematological malignancies including Chronic Myeloid Leukemia (CML) can be accurately made. However, prediction of treatment response and estimation of disease survival period eludes the currently available tools for patient… read more here.
Keywords: medicine; cml; response; analysis ... See more keywords
Assessment of the HScore as a predictor of disease outcome in patients with COVID-19
Sign Up to like & getrecommendations! Published in 2021 at "BMC Pulmonary Medicine"
DOI: 10.1186/s12890-021-01706-0
Abstract: Severe coronavirus disease 2019 (COVID-19) accompanies hypercytokinemia, similar to secondary hemophagocytic lymphohistiocytosis (sHLH). We aimed to find if HScore could predict disease severity in COVID-19. HScore was calculated in hospitalized children and adult patients with… read more here.
Keywords: assessment hscore; predictor disease; hscore; disease outcome ... See more keywords
Immunopeptidome Diversity in Chronic Lymphocytic Leukemia Identifies Patients with Favorable Disease Outcome
Sign Up to like & getrecommendations! Published in 2022 at "Cancers"
DOI: 10.3390/cancers14194659
Abstract: Simple Summary Immunosurveillance of cancer is mediated by T cell-based recognition of tumor-associated antigens, i.e., short peptides that are presented on the surface of cells on human leukocyte antigen (HLA) molecules. This encourages the analysis… read more here.
Keywords: cell; favorable disease; lymphocytic leukemia; chronic lymphocytic ... See more keywords
Disease Outcome and Brain Metabolomics of Cyclophilin-D Knockout Mice in Sepsis
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23020961
Abstract: Sepsis-associated encephalopathy (SAE) is a diffuse brain dysfunction resulting from a systemic inflammatory response to infection, but the mechanism remains unclear. The mitochondrial permeability transition pore (MPTP) could play a central role in the neuronal… read more here.
Keywords: sepsis; outcome brain; cypd; brain metabolomics ... See more keywords
Cryptococcus neoformans Genotypic Diversity and Disease Outcome among HIV Patients in Africa
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Fungi"
DOI: 10.3390/jof8070734
Abstract: Cryptococcal meningoencephalitis, a disease with poor patient outcomes, remains the most prevalent invasive fungal infection worldwide, accounting for approximately 180,000 deaths each year. In several areas of sub-Saharan Africa with the highest HIV prevalence, cryptococcal… read more here.
Keywords: neoformans genotypic; outcome; disease; among hiv ... See more keywords
Gut barrier failure biomarkers are associated with poor disease outcome in patients with primary sclerosing cholangitis
Sign Up to like & getrecommendations! Published in 2017 at "World Journal of Gastroenterology"
DOI: 10.3748/wjg.v23.i29.5412
Abstract: AIM To assess the prevalence of a panel of serologic markers that reflect gut barrier dysfunction in a mixed cohort of pediatric and adult primary sclerosing cholangitis (PSC) patients. METHODS Sera of 67 PSC patients… read more here.
Keywords: poor disease; igg; iga; aaa iga ... See more keywords
The relationship between MMP-2 rs243865, MMP-9 rs398242 and CXCL-12 rs1801157 gene polymorphisms with Japanese encephalitis disease and disease outcome in North Indian population
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Vector Borne Diseases"
DOI: 10.4103/0972-9062.361176
Abstract: Background & objectives: Japanese encephalitis virus (JEV) is one of the most important causes of acute and uncontrolled inflammatory disease in Asia. Matrix metalloproteinases (MMPs) and chemokines play a detrimental role in the host response… read more here.
Keywords: disease; north indian; mmp; gene ... See more keywords