Innate immunity to orthohantaviruses: could divergent immune interactions explain host-specific disease outcomes?
Sign Up to like & getrecommendations! Published in 2021 at "Journal of molecular biology"
DOI: 10.1016/j.jmb.2021.167230
Abstract: The genus Orthohantavirus (family Hantaviridae, order Bunyavirales) consists of numerous genetic and pathologically distinct viral species found within rodent and mammalian insectivore populations world-wide. Although reservoir hosts experience persistent asymptomatic infection, numerous rodent-borne orthohantaviruses cause… read more here.
Keywords: innate immunity; host; immune response; innate immune ... See more keywords
Seeking the optimal schedule for chickenpox vaccination in Canada: Using an agent-based model to explore the impact of dose timing, coverage and waning of immunity on disease outcomes.
Sign Up to like & getrecommendations! Published in 2019 at "Vaccine"
DOI: 10.1016/j.vaccine.2019.10.065
Abstract: Many countries continue to consider implementing a universal chickenpox vaccine program; however, there is no consensus on the most appropriate and effective timing between vaccine doses. The chickenpox vaccine schedule debate is highlighted in Canada,… read more here.
Keywords: vaccine; schedule; disease outcomes; chickenpox vaccination ... See more keywords
P166 Impact of consultation frequency and time to diagnosis on subsequent Inflammatory Bowel Disease outcomes
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Crohn's and Colitis"
DOI: 10.1093/ecco-jcc/jjab076.293
Abstract: The impact of length of time between the point of initial contact, at symptom onset, with a health-care provider and diagnosis of inflammatory bowel disease (IBD) on subsequent disease outcomes, is unclear. Diagnosis can be… read more here.
Keywords: diagnosis; time diagnosis; disease outcomes; consultation ... See more keywords
Inflammatory bowel disease and associated cardiovascular disease outcomes: A systematic review
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DOI: 10.1097/md.0000000000032775
Abstract: Background: There is limited and conflicting data available regarding the cardiovascular disease outcomes associated with inflammatory bowel disease (IBD). Objective: We aim to perform a systematic review to evaluate the cardiovascular outcomes and mortality associated… read more here.
Keywords: disease outcomes; cardiovascular disease; disease; ibd patients ... See more keywords
Cytokines and Signaling Networks Regulating Disease Outcomes in Leishmaniasis
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DOI: 10.1128/iai.00248-22
Abstract: Cytokines play crucial roles in commencing and coordinating the organized recruitment and activation of immune cells during infection. These molecular regulators play an important part in deciding the fate of disease outcomes in leishmaniasis, a… read more here.
Keywords: cytokines signaling; disease outcomes; signaling networks; disease ... See more keywords
Improving Chronic Disease Outcomes Through Medication Therapy Management in Federally Qualified Health Centers
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Primary Care & Community Health"
DOI: 10.1177/2150131917701797
Abstract: Introduction: Appropriate management of chronic diseases, including proper use of medications, can lead to better disease control, decrease disease-related complications, and improve overall health. Pharmacists have been shown to positively affect chronic disease outcomes through… read more here.
Keywords: chronic disease; disease; management; medication ... See more keywords
Type 2 Diabetes Partitioned Polygenic Scores Associate With Disease Outcomes in 454,193 Individuals Across 13 Cohorts
Sign Up to like & getrecommendations! Published in 2022 at "Diabetes Care"
DOI: 10.2337/dc21-1395
Abstract: OBJECTIVE Type 2 diabetes (T2D) has heterogeneous patient clinical characteristics and outcomes. In previous work, we investigated the genetic basis of this heterogeneity by clustering 94 T2D genetic loci using their associations with 47 diabetes-related… read more here.
Keywords: disease outcomes; type diabetes; partitioned polygenic; polygenic scores ... See more keywords
Association of Molecular Biomarker Heterogeneity With Treatment Pattern and Disease Outcomes in Multifocal or Multicentric Breast Cancer
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.833093
Abstract: Purpose This study aimed to evaluate the rates of estrogen receptor (ER), progesterone receptor (PR), human epidermal growth factor receptor 2 (HER2), and Ki67 heterogeneity in multifocal or multicentric breast cancer (MMBC) and its association… read more here.
Keywords: heterogeneity; disease outcomes; group; treatment ... See more keywords
Adipokines as Diagnostic and Prognostic Markers for the Severity of COVID-19
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DOI: 10.3390/biomedicines11051302
Abstract: Accumulating evidence implicates obesity as a risk factor for increased severity of disease outcomes in patients infected with severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2). Obesity is associated with adipose tissue dysfunction, which not… read more here.
Keywords: disease outcomes; disease; covid; prognostic markers ... See more keywords
COVID-19 Disease and Outcomes among Critically Ill Patients: The Case of Medical Nutritional Therapy
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DOI: 10.3390/nu14071416
Abstract: The recent COVID-19 pandemic, which resulted from SARS CoV-2 coronavirus infection, contributed toa rapid increasein hospital and intensive care unit (ICU) admissions [...] read more here.
Keywords: disease outcomes; ill patients; among critically; critically ill ... See more keywords