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   Articles with "disease pathogenesis" as a keyword



Phase Separation in Biological Systems: Implications for Disease Pathogenesis

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recommendations! Published in 2025 at "ChemBioChem"

DOI: 10.1002/cbic.202400883

Abstract: Phase separation is the phenomenon where distinct liquid phases, within solution, play a critical role in the organization and function of biomolecular condensates within cells. Dysregulation of phase separation has been implicated, which can be… read more here.

Keywords: phase separation; phase; separation biological; disease pathogenesis ... See more keywords

RAG deficiencies: Recent advances in disease pathogenesis and novel therapeutic approaches

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recommendations! Published in 2021 at "European Journal of Immunology"

DOI: 10.1002/eji.202048880

Abstract: The RAG1 and RAG2 proteins initiate the process of V(D)J recombination and therefore play an essential role in adaptive immunity. While null mutations in the RAG genes cause severe combined immune deficiency with lack of… read more here.

Keywords: disease pathogenesis; deficiencies recent; rag deficiencies; pathogenesis novel ... See more keywords

Early‐Onset Osteoporosis: Rare Monogenic Forms Elucidate the Complexity of Disease Pathogenesis Beyond Type I Collagen

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recommendations! Published in 2022 at "Journal of Bone and Mineral Research"

DOI: 10.1002/jbmr.4668

Abstract: Early‐onset osteoporosis (EOOP), characterized by low bone mineral density (BMD) and fractures, affects children, premenopausal women and men aged read more here.

Keywords: bone; monogenic forms; rare monogenic; disease pathogenesis ... See more keywords

miRNA in Parkinson's disease: From pathogenesis to theranostic approaches

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recommendations! Published in 2022 at "Journal of Cellular Physiology"

DOI: 10.1002/jcp.30932

Abstract: Parkinson's disease (PD) is an age associated neurological disorder which is specified by cardinal motor symptoms such as tremor, stiffness, bradykinesia, postural instability, and non‐motor symptoms. Dopaminergic neurons degradation in substantia nigra region and aggregation… read more here.

Keywords: pathogenesis theranostic; disease pathogenesis; mirna parkinson; parkinson disease ... See more keywords

Parkinson’s disease pathogenesis from the viewpoint of small fish models

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recommendations! Published in 2017 at "Journal of Neural Transmission"

DOI: 10.1007/s00702-017-1772-1

Abstract: Parkinson’s disease is a neurodegenerative disorder that involves movement discloses, degeneration of dopaminergic neurons, and presence of cytoplasmic inclusion bodies. Various animal models have been developed and small fish including zebrafish and medaka fish have… read more here.

Keywords: models parkinson; fish models; disease pathogenesis; small fish ... See more keywords

Diabetes Mellitus and Associated Vascular Disease: Pathogenesis, Complications, and Evolving Treatments

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recommendations! Published in 2025 at "Advances in Therapy"

DOI: 10.1007/s12325-025-03185-9

Abstract: Diabetes mellitus is a metabolic disorder, characterized by elevated blood sugar levels (hyperglycemia) and insulin dysregulation. This disease is associated with morbidity and mortality, including significant potential vascular complications. High levels of hyperglycemia lead to… read more here.

Keywords: associated vascular; disease; diabetes mellitus; vascular disease ... See more keywords

IL‐36&ggr; induces a transient HSV‐2 resistant environment that protects against genital disease and pathogenesis

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recommendations! Published in 2018 at "Cytokine"

DOI: 10.1016/j.cyto.2018.07.034

Abstract: HighlightsHSV‐2 infection induces IL‐36&ggr; expression in human vaginal epithelial cells.HSV‐2 replication is limited by IL‐36&ggr; treatment in vitro and in vivo.IL‐36&ggr; induces immune mediators and PMN recruitment in the vaginal epithelium.Treatment with IL‐36&ggr; protects against… read more here.

Keywords: hsv; disease pathogenesis; treatment; infection ... See more keywords
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Castleman Disease Pathogenesis.

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recommendations! Published in 2018 at "Hematology/oncology clinics of North America"

DOI: 10.1016/j.hoc.2017.09.002

Abstract: Castleman disease (CD) describes a group of heterogeneous disorders with common lymph node histopathologic features, including atrophic or hyperplastic germinal centers, prominent follicular dendritic cells, hypervascularization, polyclonal lymphoproliferation, and/or polytypic plasmacytosis. The cause and pathogenesis… read more here.

Keywords: hematology; disease pathogenesis; pathogenesis; castleman disease ... See more keywords
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Burden and disease pathogenesis of influenza and other respiratory viruses in diabetic patients.

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recommendations! Published in 2022 at "Journal of infection and public health"

DOI: 10.1016/j.jiph.2022.03.002

Abstract: Over the past two decades, diabetes mellitus (DM) has been receiving increasing attention among autoimmune diseases. The prevalence of type 1 and type 2 diabetes has increased rapidly and has become one of the leading… read more here.

Keywords: disease pathogenesis; respiratory viruses; influenza; diabetic patients ... See more keywords
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Genetics of Alzheimer’s disease: From pathogenesis to clinical usage

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recommendations! Published in 2017 at "Journal of Clinical Neuroscience"

DOI: 10.1016/j.jocn.2017.06.074

Abstract: Alzheimer's disease (AD) is the most common type of dementia and has caused a major global health concern. Understanding the etiology of AD can be beneficial for the diagnosis and intervention of this disease. Genetics… read more here.

Keywords: disease pathogenesis; alzheimer disease; genetics; pathogenesis ... See more keywords
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A New Chapter in Genetic Medicine: RNA Editing and its Role in Disease Pathogenesis.

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recommendations! Published in 2018 at "Trends in molecular medicine"

DOI: 10.1016/j.molmed.2018.01.002

Abstract: The transfer of genomic information from DNA to mRNA to protein usually occurs with high fidelity, but can also be subverted by a programmed RNA sequence alteration termed 'RNA editing', involving deamination of adenosine to… read more here.

Keywords: medicine; disease pathogenesis; new chapter; rna editing ... See more keywords