Tau in Alzheimer’s Disease: Pathological Alterations and an Attractive Therapeutic Target
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DOI: 10.1007/s11596-020-2282-1
Abstract: Alzheimer’s disease (AD) is an age-related neurodegenerative disease with two major hallmarks: extracellular amyloid plaques made of amyloid-β (Aβ) and intracellular neurofibrillary tangles (NFTs) of abnormally hyperphosphorylated tau. The number of NFTs correlates positively with… read more here.
Keywords: pathological alterations; disease pathological; tau alzheimer; alzheimer disease ... See more keywords
Potential of extracellular vesicles in the Parkinson's disease – Pathological mediators and biomarkers
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DOI: 10.1016/j.neuint.2021.104974
Abstract: Parkinson's disease (PD) is an age-related neurodegenerative disorder characterized by the progressive deterioration of motor function. Histopathologically, it is widely accepted that the progressive death of selected dopaminergic neuronal populations and the accumulation of hallmark… read more here.
Keywords: extracellular vesicles; disease pathological; potential extracellular; parkinson disease ... See more keywords
Current Status of Alzheimer's Disease and Pathological Mechanisms Investigating the Therapeutic Molecular Targets.
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DOI: 10.2174/1566524022666220404112843
Abstract: Alzheimer's disease (AD) is a sort of disarrangement in psychological, biological, or developmental mechanisms basic to mental functions. AD is generally affiliated with marked discomfort and impaired social, professional, or other crucial aspects of life.… read more here.
Keywords: disease pathological; pathological mechanisms; disease; alzheimer disease ... See more keywords