Recent Development in Celiac Disease: Pathophysiology, Animal Models and Treatments
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DOI: 10.1002/ddr.70149
Abstract: Celiac disease (CD) is an autoimmune disorder which is triggered by gluten in genetically susceptible individuals. There is no successful therapy for CD. A strict gluten‐free diet (GFD) is the only remedy used in clinical… read more here.
Keywords: disease; recent development; disease pathophysiology; development celiac ... See more keywords
Strictures in Crohn’s Disease: From Pathophysiology to Treatment
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DOI: 10.1007/s10620-020-06227-0
Abstract: Despite recent advances aimed to treat transmural inflammation in Crohn’s disease (CD) patients, the progression to a structuring behavior still represents an issue for clinicians. As inflammation becomes chronic and severe, the attempt to repair… read more here.
Keywords: strictures crohn; pathophysiology treatment; disease; disease pathophysiology ... See more keywords
Comparison of the decreases in regional cerebral blood flow in the posterior cingulate cortex, precuneus, and parietal lobe between suspected non‐Alzheimer's disease pathophysiology and Alzheimer's disease
Sign Up to like & getrecommendations! Published in 2021 at "Psychogeriatrics"
DOI: 10.1111/psyg.12729
Abstract: Suspected non‐Alzheimer's disease pathophysiology (SNAP) shows Alzheimer's disease (AD)‐like neurodegeneration; however, amyloid β, which is a biological marker in AD, remains within normal levels. Since the effectiveness of anti‐dementia drugs for AD on SNAP is… read more here.
Keywords: decreases regional; suspected non; alzheimer disease; disease ... See more keywords
A spatial atlas of human gastrointestinal acute GVHD reveals epithelial and immune dynamics underlying disease pathophysiology.
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DOI: 10.1126/scitranslmed.adu6032
Abstract: Acute graft-versus-host disease (aGVHD) is a severe complication of allogeneic hematopoietic stem cell transplantation, driven by alloreactive donor T cells in the gut. However, the roles of additional donor and host cells in this process… read more here.
Keywords: disease; immune dynamics; spatial atlas; across individuals ... See more keywords
Mitochondrial Dysfunction and Cardiovascular Disease: Pathophysiology and Emerging Therapies
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DOI: 10.1155/2022/9530007
Abstract: Mitochondria ensure the supply of cellular energy through the production of ATP via oxidative phosphorylation. The alteration of this process, called mitochondrial dysfunction, leads to a reduction in ATP and an increase in the production… read more here.
Keywords: cardiovascular disease; disease pathophysiology; mitochondrial dysfunction; dysfunction ... See more keywords
Pathophysiology and pharmacological management for sleep problems in Parkinson's disease.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Parkinson's disease"
DOI: 10.1177/1877718x251371945
Abstract: Sleep problems are among the most frequently reported non-motor symptoms of Parkinson's disease (PD), with a broad range of disorders: insomnia, REM sleep behavior disorder, restless legs syndrome, excessive daytime sleepiness, and sleep-related breathing disorders.… read more here.
Keywords: sleep problems; pathophysiology pharmacological; disease pathophysiology; sleep ... See more keywords
Bile Acids in Inflammatory Bowel Disease: From Pathophysiology to Treatment
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DOI: 10.3390/biomedicines12122910
Abstract: Inflammatory bowel disease (IBD) is a chronic condition that affects about 7 million people worldwide, and new therapies are needed. Understanding the complex roles that bile acids (BAs) play in IBD may lead to the… read more here.
Keywords: bile acids; disease; disease pathophysiology; bowel disease ... See more keywords