Autoreactive IgG and IgA B Cells Evolve through Distinct Subclass Switch Pathways in the Autoimmune Disease Pemphigus Vulgaris
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DOI: 10.1016/j.celrep.2018.07.093
Abstract: SUMMARY Lineage analysis of autoreactive B cells can reveal the origins of autoimmunity. In the autoimmune disease pemphigus vulgaris (PV), desmoglein 3 (DSG3) and DSG1 autoantibodies are predominantly of the IgG4 subclass and less frequently… read more here.
Keywords: pemphigus vulgaris; disease pemphigus; iga; autoimmune disease ... See more keywords
Individuals With the Rare Disease Pemphigus: A Quest for Diagnostic
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DOI: 10.1177/1049732318803590
Abstract: This qualitative study conducted in France of “individuals living with a pemphigus” (ILPs; N = 54) highlights the taxing diagnostic trajectory of those suffering from these rare autoimmune diseases. Beyond enduring a diagnostic period that… read more here.
Keywords: disease pemphigus; pemphigus quest; rare disease; quest diagnostic ... See more keywords