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Disease protection by DNA damage responses induced by anthracyclines

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0 Published in 2018 at "Free Radical Biology and Medicine"

DOI: 10.1016/j.freeradbiomed.2018.04.162

Abstract: We have identified the anthracycline family of chemotherapeutic drugs (epirubicin, doxorubicin and daunorubicin) as potent antagonists of inflammatory cytokine production that are able to confer strong protection in a mouse model of severe sepsis. We… read more here.

Keywords: dna damage; disease protection; damage;

Unbiased identification of anthracycline-mediated disease protection mechanisms

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0 Published in 2018 at "Free Radical Biology and Medicine"

DOI: 10.1016/j.freeradbiomed.2018.04.176

Abstract: Anthracyclines, a class of chemotherapeutic drugs that includes epirubicin, doxorubicin and daunorubicin, induce inflammatory cytokines in an in vitro model of inflammation. In vivo, these drugs are strongly protective in the cecal ligation and puncture… read more here.

Keywords: anthracycline mediated; dna damage; protection; disease protection ... See more keywords

Ubiquitin and Ubiquitin-like proteins in cardiac disease and protection.

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0 Published in 2018 at "Current drug targets"

DOI: 10.2174/1389450117666151209114608

Abstract: Post-translational modification represents an important mechanism to regulate protein function in cardiac cells. Ubiquitin (Ub) and ubiquitin-like proteins (UBLs) are a family of protein modifiers that share a certain extent of sequence and structure similarity.… read more here.

Keywords: like proteins; ubiquitin like; cardiac disease; disease protection ... See more keywords

The crosstalk between STAT3 and microRNA in cardiac diseases and protection

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2 Published in 2022 at "Frontiers in Cardiovascular Medicine"

DOI: 10.3389/fcvm.2022.986423

Abstract: Signal transducer and activator of transcription 3 (STAT3), an important transcription factor and signaling molecule, play an important role in cardiac disease and protection. As a transcription factor, STAT3 upregulates anti-oxidative and anti-apoptotic genes but… read more here.

Keywords: cardiac disease; protection; cardiac diseases; stat3 ... See more keywords

Human Breast Milk: From Food to Active Immune Response With Disease Protection in Infants and Mothers

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1 Published in 2022 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2022.849012

Abstract: Breastfeeding is associated with long-term wellbeing including low risks of infectious diseases and non-communicable diseases such as asthma, cancer, autoimmune diseases and obesity during childhood. In recent years, important advances have been made in understanding… read more here.

Keywords: human breast; breast milk; disease protection; milk ... See more keywords