Clinical and Incidental Perineural Invasion of Cutaneous Squamous Cell Carcinoma: A Systematic Review and Pooled Analysis of Outcomes Data
Sign Up to like & getrecommendations! Published in 2017 at "JAMA Dermatology"
DOI: 10.1001/jamadermatol.2017.1680
Abstract: Importance Perineural invasion (PNI) in cutaneous squamous cell carcinoma (CSCC) has been associated with an increased risk of poor outcomes. Patients with PNI may present with clinical symptoms and/or radiologic evidence of PNI (clinical PNI… read more here.
Keywords: disease specific; recurrence; dermatology; disease ... See more keywords
Consumer Assessment of Healthcare Providers and Systems Among Racial and Ethnic Minority Patients With Alzheimer Disease and Related Dementias
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.33436
Abstract: This cross-sectional study evaluates racial and ethnic disparities in Consumer Assessement of Healthcare Providers and Systems measures among patients with Alzheimer Disease and related dementias. read more here.
Keywords: healthcare providers; disease related; alzheimer disease; racial ethnic ... See more keywords
Associations Between Neuropsychiatric Symptoms and Neuropathological Diagnoses of Alzheimer Disease and Related Dementias.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA psychiatry"
DOI: 10.1001/jamapsychiatry.2021.4363
Abstract: Importance Understanding associations of Alzheimer disease (AD) and related dementias (ADRD) pathologies with common neuropsychiatric symptoms (NPS) may have implications for diagnosis and management. Objective To evaluate ADRD neuropathological diagnoses and NPS without consideration of… read more here.
Keywords: neuropsychiatric symptoms; related dementias; disease; pathology ... See more keywords
Expression of disease‐related miRNAs in white‐matter lesions of progressive multiple sclerosis brains
Sign Up to like & getrecommendations! Published in 2019 at "Annals of Clinical and Translational Neurology"
DOI: 10.1002/acn3.750
Abstract: MicroRNA (miRNA) expression in the serum of multiple sclerosis (MS) patients has been correlated with white matter (WM) magnetic resonance imaging (MRI) abnormalities. The expression levels and cellular specificity of the target genes of these… read more here.
Keywords: multiple sclerosis; expression disease; disease related; white matter ... See more keywords
Modeling Parkinson's disease‐related symptoms in alpha‐synuclein overexpressing mice
Sign Up to like & getrecommendations! Published in 2022 at "Brain and Behavior"
DOI: 10.1002/brb3.2628
Abstract: Intracellular deposition of alpha‐synuclein (α‐syn) as Lewy bodies and Lewy neurites is a central event in the pathogenesis of Parkinson's disease (PD) and other α‐synucleinopathies. Transgenic mouse models overexpressing human α‐syn, are useful research tools… read more here.
Keywords: related symptoms; disease related; modeling parkinson; parkinson disease ... See more keywords
Disease‐related thrombocytopenia in myelofibrosis is defined by distinct genetic etiologies and is associated with unique prognostic correlates
Sign Up to like & getrecommendations! Published in 2022 at "Cancer"
DOI: 10.1002/cncr.34414
Abstract: Thrombocytopenia in patients with myelofibrosis (MF) is prognostically detrimental and poses a therapeutic challenge. MF patients with thrombocytopenia are considered high‐risk by most prognostic models and their distinct phenotype has given rise to the emerging… read more here.
Keywords: related thrombocytopenia; distinct genetic; disease related; thrombocytopenia myelofibrosis ... See more keywords
Disease‐related population declines in bats demonstrate non‐exchangeability in generalist predators
Sign Up to like & getrecommendations! Published in 2022 at "Ecology and Evolution"
DOI: 10.1002/ece3.8978
Abstract: Abstract The extent to which persisting species may fill the functional role of extirpated or declining species has profound implications for the structure of biological communities and ecosystem functioning. In North America, arthropodivorous bats are… read more here.
Keywords: disease related; population declines; bat; generalist predators ... See more keywords
Healthcare use patterns before Alzheimer's disease and related diseases identification and future healthcare trajectory
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Geriatric Psychiatry"
DOI: 10.1002/gps.5849
Abstract: A frequent late Alzheimer's Disease and Related Diseases (ADRD) identification is described and may induce erratic health resource use. We aimed to describe healthcare use patterns preceding ADRD identification. read more here.
Keywords: disease related; alzheimer disease; identification; related diseases ... See more keywords
Thermal Shift and Stability Assays of Disease-Related Misfolded Proteins Using Differential Scanning Fluorimetry.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-8820-4_16
Abstract: Systematic identification of buffer formulations and small molecule chaperones that improve the expression, stability, and storage of proteins with therapeutic interest has gained enormous importance in biochemical research as well as in biotechnology and biomedical… read more here.
Keywords: thermal shift; differential scanning; scanning fluorimetry; stability ... See more keywords
Genetic associations of breast and prostate cancer are enriched for regulatory elements identified in disease-related tissues
Sign Up to like & getrecommendations! Published in 2019 at "Human Genetics"
DOI: 10.1007/s00439-019-02041-5
Abstract: Although genome-wide association studies (GWAS) have identified hundreds of risk loci for breast and prostate cancer, only a few studies have characterized the GWAS association signals across functional genomic annotations with a particular focus on… read more here.
Keywords: cancer; disease related; breast prostate; prostate cancer ... See more keywords
Coping Strategies Utilized by Middle-Aged and Older Latino Caregivers of Loved Ones with Alzheimer's Disease and Related Dementia.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of cross-cultural gerontology"
DOI: 10.1007/s10823-019-09390-8
Abstract: We aimed to explore the coping strategies utilized by Latino caregivers of people with Alzheimer's disease or related dementia (ADRD). We conducted 16 semi-structured interviews with Latinos family caregivers. The interviews explored the caregivers' experiences… read more here.
Keywords: alzheimer disease; latino caregivers; related dementia; coping strategies ... See more keywords