MicroPattern: a web-based tool for microbe set enrichment analysis and disease similarity calculation based on a list of microbes
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/srep40200
Abstract: The microbiota colonized on human body is renowned as “a forgotten organ” due to its big impacts on human health and disease. Recently, microbiome studies have identified a large number of microbes differentially regulated in… read more here.
Keywords: microbe; list microbes; disease; disease similarity ... See more keywords
CoGO: a contrastive learning framework to predict disease similarity based on gene network and ontology structure
Sign Up to like & getrecommendations! Published in 2022 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btac520
Abstract: MOTIVATION Quantifying the similarity of human diseases provides guiding insights to the discovery of micro-scope mechanisms from a macro scale. Previous work demonstrated that better performance can be gained by integrating multi-view data sources or… read more here.
Keywords: learning; gene; disease similarity; ontology ... See more keywords
Constructing Disease Similarity Networks Based on Disease Module Theory
Sign Up to like & getrecommendations! Published in 2020 at "IEEE/ACM Transactions on Computational Biology and Bioinformatics"
DOI: 10.1109/tcbb.2018.2817624
Abstract: Quantifying the associations between diseases is now playing an important role in modern biology and medicine. Actually discovering associations between diseases could help us gain deeper insights into pathogenic mechanisms of complex diseases, thus could… read more here.
Keywords: disease module; biology; module theory; disease similarity ... See more keywords
MultiSourcDSim: an integrated approach for exploring disease similarity
Sign Up to like & getrecommendations! Published in 2019 at "BMC Medical Informatics and Decision Making"
DOI: 10.1186/s12911-019-0968-8
Abstract: Background A collection of disease-associated data contributes to study the association between diseases. Discovering closely related diseases plays a crucial role in revealing their common pathogenic mechanisms. This might further imply treatment that can be… read more here.
Keywords: disease similarity; data sources; similarity; disease ... See more keywords
A disease similarity matrix based on the uniqueness of shared genes
Sign Up to like & getrecommendations! Published in 2017 at "BMC Medical Genomics"
DOI: 10.1186/s12920-017-0265-2
Abstract: BackgroundComplex diseases involve many genes, and these genes are often associated with several different illnesses. Disease similarity measurement can be based on shared genotype or phenotype. Quantifying relationships between genes can reveal previously unknown connections… read more here.
Keywords: ontology; disease similarity; similarity; disease ... See more keywords