Complement Evasion by Lyme Disease Spirochetes.
Sign Up to like & getrecommendations! Published in 2020 at "Trends in microbiology"
DOI: 10.1016/j.tim.2020.05.004
Abstract: The complement system is an ancient arm of the innate immune system that plays important roles in pathogen recognition and elimination. Upon activation by microbes, complement opsonizes bacterial surfaces, recruits professional phagocytes, and causes bacteriolysis.… read more here.
Keywords: complement; disease spirochetes; complement evasion; lyme disease ... See more keywords
Interference with LTβR signaling by tick saliva facilitates transmission of Lyme disease spirochetes
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2208274119
Abstract: Significance Among vectors, ticks transmit the most diverse human and animal pathogens, leading to an increasing number of new challenges worldwide. In this study, we found that Ltbr knockout mice were more susceptible to Lyme… read more here.
Keywords: disease; lyme disease; disease spirochetes; transmission ... See more keywords
Further Insights Into the Interaction of Human and Animal Complement Regulator Factor H With Viable Lyme Disease Spirochetes
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Veterinary Science"
DOI: 10.3389/fvets.2018.00346
Abstract: Spirochetes belonging to the Borrelia (B.) burgdorferi sensu lato (s.l.) complex differ in their ability to establish infection and to survive in diverse vertebrate hosts. Association with and adaption to various hosts most likely correlates… read more here.
Keywords: complement regulator; regulator factor; disease spirochetes; lyme disease ... See more keywords