Spinal manifestations of CLN1 disease start during the early postnatal period
Sign Up to like & getrecommendations! Published in 2020 at "Neuropathology and Applied Neurobiology"
DOI: 10.1111/nan.12658
Abstract: To understand the progression of CLN1 disease and develop effective therapies we need to characterize early sites of pathology. Therefore, we performed a comprehensive evaluation of the nature and timing of early CLN1 disease pathology… read more here.
Keywords: manifestations cln1; disease start; pathology; cln1 disease ... See more keywords
Does Parkinson's disease start in the gut?
Sign Up to like & getrecommendations! Published in 2018 at "Arquivos de neuro-psiquiatria"
DOI: 10.1590/0004-282x20170188
Abstract: Current understanding of the pathophysiology of Parkinson's disease suggests a key role of the accumulation of alpha-synuclein in the pathogenesis. This critical review highlights major landmarks, hypotheses and controversies about the origin and progression of… read more here.
Keywords: parkinson; disease start; start gut; parkinson disease ... See more keywords